ATG8 IS ESSENTIAL SPECIFICALLY FOR AN AUTOPHAGY-INDEPENDENT FUNCTION IN APICOPLAST BIOGENESIS IN BLOOD-STAGE MALARIA PARASITES

ATG8 Is Essential Specifically for an Autophagy-Independent Function in Apicoplast Biogenesis in Blood-Stage Malaria Parasites

ABSTRACT Plasmodium parasites and related pathogens contain an essential nonphotosynthetic plastid organelle, L-Methionine the apicoplast, derived from secondary endosymbiosis.Intriguingly, a highly conserved eukaryotic protein, autophagy-related protein 8 (ATG8), has an autophagy-independent function in the apicoplast.Little is known about the nov

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The Utility of a Brief Web-Based Prevention Intervention as a Universal Approach for Risky Alcohol Use in College Students: Evidence of Moderation by Family History

Background: Alcohol use on college campuses is prevalent and contributes to problems that affect the health, emotional wellbeing, and academic success of college students.Risk factors, such as family history of alcohol problems, swim wear predict future alcohol problems, but less is known about their potential impact on intervention effectiveness.T

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Histopathological and Immunohistochemical Evaluation of Meningiomas with Reference to Proliferative Markers p53 and Ki-67

Introduction: Meningiomas are slow growing primary central nervous system (CNS) tumours attached to the duramater, which arise from the meningothelial cells of the arachnoid.Grading of meningioma based on histological findings assisted with supplementary immunohistochemical studies, predicts the prognosis of meningioma with good precision.Aim: To e

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Correlation between measured and calculated free phenytoin serum concentration in neurointensive care patients with hypoalbuminemia

Seyyede-Sareh Javadi,1 Reza Mahjub,2 Abbas Taher,3 Younes Mohammadi,4 Maryam Mehrpooya1 1Department of Clinical Pharmacy, School of Pharmacy, Hamadan University of Medical Sciences, Hamadan, Iran; 2Department of Pharmaceutics, School of Pharmacy, Hamadan University of Medical Sciences, Hamadan, Iran; 3Department of Anesthesiology and Critical Care,

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